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KMID : 0388019940050030049
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Korean Journal Gynecologic Oncology and Colposcopy
1994 Volume.5 No. 3 p.49 ~ p.53
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Flow Cytometric DNA Coatent Analysis in Uterine Cervical Cancer
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Abstract
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The DNA ploidy using fresh tissues from 304 cervical cancer were analyzed by flow cytometry in order to evaluate the correlation between DNA ploidy patterns and prognostic factors of uterine cervical cancer.
There were 167 diploid cases(55%) and 137 aneuploid(45%). No significant correlation was noted in stage, age and lymph node metastases between diploid tumor. But S-phase fraction and DNA index were higher slightly in cases of lymph node
metastases
compaired to non-metastases.
This results suggest that the DNA ploidy cannot be used as an independent prognostic factor, but further evaluation will be needed in order to conclude definite relationship between prognostic factor and S-phase fraction or DNA index.
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